Early Enabling Formulation Development

Developing robust preclinical formulations provides multiple benefits:

• Enhanced solubility and bioavailability: Overcome challenges with poorly soluble APIs using nanoemulsion techniques and excipient optimization.
• Optimized drug delivery: Tailored dosage formulations of drugs for specific delivery systems, including injectable formulations and oral solid dosage forms.
• Shortened timelines: Streamlined processes to advance toxicology studies and pharmacokinetic studies, accelerating progression to clinical trials.
• Risk mitigation: Comprehensive preclinical in-vitro testing identifies and addresses potential issues early.

At Solitek, we utilize state-of-the-art methodologies to address the complexities of early formulation development:

• Excipient Screening: Rapid evaluation of excipients to enhance solubility and stability, even in high-protein formulations.
• Particle Reduction: Leveraging formulation of nanoemulsion techniques to improve bioavailability for poorly soluble APIs.
• Preclinical Formulation Design: Creating robust formulations of pharmaceutical solutions to ensure consistent results in early studies.
• Customized Solutions: Tailoring API formulation strategies to align with specific drug and study requirements.
• In Vitro Testing: Comprehensive analysis under bio-relevant conditions to validate formulation performance.

Our Early Enabling Formulation Development services are pivotal in various areas of preclinical drug development:

• Liquid and Injectable Formulations: Expertise in formulation development of liquid dosage forms for preclinical tox and pharmacokinetic
• Solid Oral Formulations: Developing different solid oral dose formulations to expand delivery options.

At Solitek, we understand that every drug candidate is unique. Our client-focused approach ensures that solutions are customized to meet the specific demands of your project:

• Collaborative Partnerships: Working closely with your team to align with your goals and timelines.
• Innovative Thinking: Incorporating advanced techniques to stay ahead in preclinical formulation science.
• High-Quality Results: Delivering solutions that not only meet but exceed industry standards for drug formulation development.

Partnering with Solitek ensures access to:

• Proven Expertise: Decades of experience in solving complex solid state and formulation challenges.
• Innovative Techniques: Advanced methodologies to optimize preclinical formulations.
• Commitment to Quality: Rigorous standards to ensure reproducibility and reliability.
• Comprehensive Services: From solid state characterization to early enabling formulations, we cover all aspects of preclinical development.